The Aids epidemics that does not seem to regress in Africa has a catastrophic impact on children, adolescents and adults. The consequences of such a situation are sanitary, economic and demographic. The adolescents, who are more than a billion in the world, are very concerned, particularly in Africa where only very few of them go to school and who for many of them either remain in the streets and/or prostitute themselves. Anti-Aids committees have been organized among school children and teachers, information and education in terms of prevention try to move as far as the rural villages. Associations try to help the authorities. People suffering from Aids themselves try to inform and by telling their stories promote a decline of denial and exclusion. Yet medical and psychosocial help and care should be better, for, if they weren’t, the discourse on prevention would be totally useless.